Cardiac Troponin I Should Replace CKMB for the Diagnosis of Acute Myocardial Infarction
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چکیده
منابع مشابه
Cardiac Troponin I for Diagnosis of Acute Myocardial Infarction*
Serial plasma concentrations of myoglobin, creatine kinase MB (CK-MB) isoenzyme, and cardiac troponin I (cTnl) were measured in 25 patients with a confirmed diagnosis of acute myocardial infarction (AMI), and 74 patients who were suspected of AMI but were subsequently ruled out for this diagnosis. The cutoff concentration for the cTnl assay was optimally determined to be 2.5 ng/mL. Of the three...
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Background: Acute myocardial infarction (MI) accounts for one third of deaths. Cardiac troponin I (TnI) is a reliable biomarker of cardiac muscle tissue injury and is employed in the early diagnosis of MI.Objectives: In this study, a molecular method is introduced to early diagnosis of MI by rapid detection of TnI.Materials and Methods: The detection method was based on electrochemical aptasens...
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We evaluated the analytical and clinical performance of an immunoassay for cardiac troponin T (cTnT). Within-run and total imprecision ranged from 1.6 to 11.3%. The sensitivity and linear range was 0.015 and 13 micrograms/L, respectively. Frozen samples were stable for at least 8 weeks. No interferences were seen with lipids or bilirubin (total and conjugated). Hemoglobin caused a negative bias...
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Troponin T is a structurally bound protein found in striated muscle cells. We tested concentrations of its cardiac-specific isotype in peripheral venous blood samples serially drawn from 72 patients with confirmed myocardial infarction. Fifty-nine patients received thrombolytic treatment with intravenous streptokinase, urokinase, or recombinant tissue-type plasminogen activator; because of cont...
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Patients presenting in the emergency department (ED) with chest discomfort or other symptoms suggestive of acute myocardial infarction (AMI) or unstable angina are at priority for triage and risk stratification. Their treatment is on priority basis and is time bound to have favourable outcome. The goal of door-to-needle time for patient with AMI subjected to fibrinolysis is less than 30 min, wh...
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ژورنال
عنوان ژورنال: Annals of Clinical Biochemistry: International Journal of Laboratory Medicine
سال: 1997
ISSN: 0004-5632,1758-1001
DOI: 10.1177/000456329703400503